Archives of Advanced Sciences 2018-01-29T15:25:55+00:00 Editor Open Journal Systems <p><strong> Archives of Advanced Sciences </strong>is an international scientific Open-access journal which exists to publish outcomes of investigations in the all area of sciences. Different types of scientific papers are welcomed from all countries.</p> <p><strong><span style="font-size: 11.0pt; font-family: 'Calibri',sans-serif; color: #7030a0;" lang="EN-US">ISSN 2521-3636 (Online), ISSN</span></strong> <strong><span style="font-size: 11.0pt; font-family: 'Calibri',sans-serif; color: #7030a0;" lang="EN-US">2521-3628 (Print)</span></strong></p> <p><strong>Authors can send their papers through online submissions or as an email attachment to:</strong></p> <p><strong>Indexed in</strong>:</p> <p><strong> <span class="tagline">Geneva Foundation for Medical Education and Research</span>,</strong></p> <p><strong>International Committee of Medical Journal Editors (ICMJE),</strong></p> <p><strong> Scientific world index,</strong></p> <p><strong>Academia,</strong></p> <p><strong> Science Library Index,</strong></p> <p><strong>ResearchBib,</strong></p> <p><strong> JournalGuide,</strong></p> <p><strong><strong>Google Scholar,</strong></strong></p> <p><strong><strong><span class="tagline">Scientific Indexing Services (SIS database),</span></strong></strong></p> <p><strong><strong><span class="tagline">International Innovative Journal Impact Factor</span></strong></strong></p> <p><strong>&nbsp;</strong></p> Urodynamic and Ultrasound Findings in Enuretic Children: A non-Randomized Clinical Trail 2018-01-29T15:10:52+00:00 Hamidreza Qashqai Behrouz Fadavi Morteza Fallah-karkan <p>Introduction: Because of high prevalence and important effects of nocturnal enuresis in children's life and presence of some refractory cases that are not well-responders of standard treatment, this urodynamic and ultrasound study was done in children with mono-symptomatic primary nocturnal enuresis (MSPNE) before and after six months of therapy.<br>Materials and Methods: From May 2011 to May 2015, 259 children (142 boys and 117 girls) with MSPNE according to the International Children’s Continence Society guidelines and more than three wet nights per week were chosen for this non-randomized clinical trial. They were treated with desmopressin (20 μg intra-nasally at bedtime) and enuresis alarm. Six months after the treatment we divided the participants into two groups of non-responders and well-responders and repeated the evaluations.<br>Result: Urodynamic (like low bladder compliance and capacity and bladder outlet obstruction) and ultrasound abnormalities (like high and low bladder volume and wall thickness index percentage, abnormal bladder wall thickness) were more common in the non-responder group.<br>Conclusion: Urodynamic study combined with ultrasound evaluation can be more helpful in case of refractory enuresis by detecting dysfunctional voiding, which consist of a large percentage of these patients. These investigations can be used as a predictor of treatment response and need for more evaluation or other kinds of treatments.</p> 2018-01-29T15:10:23+00:00 ##submission.copyrightStatement## Studying the Relationship between Pro BNP level with Chest X-ray Changes in Patients with Pneumonia 2018-01-29T15:25:55+00:00 Vahan Meradians Moslem Ahmadi Saeed Kalantari Mir Saeid Ramezani Ali Habibi <p><strong>Introduction</strong>: Pneumonia is the second leading cause of nosocomial infections and the most common cause of hospital death. Recently BNP (B-type natriuretic peptide) has been used as a marker for severity evaluation of community acquired Pneumonia’s (CAP) patients. The aim of this study is to determine the relationship between pro-BNP levels with chest radiographic changes during the course of treatment of patients with Pneumonia.</p> <p><strong>Materials and Methods</strong>: This cross-sectional study was carried out on 30 patients with CAP in Hazrat-e Rasoul Hospital of Tehran in the year 2016. Demographic data, Laboratory findings including ProBNP level and Chest Radiographic findings were recorded. Data were analyzed then using SPSS&nbsp; software ,version 20.</p> <p><strong>Result</strong>: Out of thirty patients, 43.3% (13 cases) were male and 56.7% (17 cases) were female. Patients were at the age of 25 to 85 years old. The mean age of patients was 64.63 ± 14.40. The baseline BNP level and the level of BNP six weeks after treatment were 237.77 ± 160.95 and 226.33 ± 156.74, respectively. There was no significant difference between baseline BNP level and the level of BNP six weeks after treatment (P=0.236). After treatment, 90% of patients were cleared from chest involvement. There was a significant difference between the areas of lung involvement during the measurement of baseline BNP level with the level of BNP six weeks after treatment (P &lt;0.001).</p> <p><strong>Conclusion</strong>: There was no significant difference between the level of baseline BNP and the level of BNP six weeks after treatment. After 6 weeks treatment, there was no evidence of chest involvement in most patients. The lack of significant correlation between BNP levels and the severity of pneumonia could be due to small sample size of the study. Therefore, it is suggested that the study to be conducted with a larger sample size and BNP levels compared with healthy individuals.</p> 2018-01-29T15:25:31+00:00 ##submission.copyrightStatement##